Pèpe's Little Napoli (Carmel-by-the-Sea, Calif.); Pica's Mexican Taqueria (Jackson, Wyo.); The Factory Gastrobar (Long Beach, Calif.).
This trip, Guy's hitting up all kinds of killer joints, from classic Italian to modern Americana. In Carmel, Cooking Channel host G. Garvin is along for the ride at an authentic Italian joint dishin' out tri-color cannelloni and fresh seafood cioppino. In Jackson, Wyo., a California chef brings his brand of legit Mexican to the mountains, like savory chicken sopes and one of Guy's favorite dishes, pozole. And in Long Beach, it's a Bixby Knolls neighborhood spot where a chef with an artistic flair is servin' up some of her signature veggie sammies and a spin on pig and grits.