Ruan Liuzheng returns to her hometown after seven years, and becomes a neurosurgeon at Beiya Hospital. However, she didn't expect to meet her ex-husband, Ning Zhiqian, who is the most experienced neurosurgeon. Ruan Liuzheng is no longer the weak and timid girl, and she shows resolute and determination in both her work and relationship. When they were in Africa to execute medical relief efforts, Ning Zhiqian was injured in a gunshot. Ruan Liuzheng didn't leave his side, and fought hard to save him from the brink of death. The two have gained a new understanding of life, and begun a new relationship again.

Peng Guanying, Wang Churan, Chuai Ni, Liu Ruilin, Mao Linlin, Li Zifeng, Zhu Jun Lin, Li Sheng Jia, Tong Jing, Tan Jiatai, Guo Yuanyuan, Wang Junren, Du Yuchen, Shi Tieying, Zhu Yin, Xiu Meng, Tao Huimin, Tian Lei, Fan Jing Yi, Yao Anlian, Ashin Shu, Sun Zhengyu, Zhang Qian, Liao Yuchen, Fang Xiaoli, Li Zhimo, Wang Shihuai, Yan Jing-Yao, Guan Yunpeng, Su Yu Jie, Liu Kejun, Zhu Weiwei, Hu Yuxuan, Du Heqian, Cao Minghua, Shi Lei, Zhao Yansong, Zhang Weina, Zhang Xiang, Ling Chen, Li Hongtao